New · Diffusion Tensor Imaging

PrecisionPlus v3™

Advanced DTI See which brain tracts are out of range.

Advanced DTI measures up to 33 major white-matter tracts against healthy reference data matched for age and sex, and flags any tract outside its normative range. It is part of the PrecisionPlus v3™ report, read and signed by a board-certified neuroradiologist.

A whole-brain tractogram, side view, with white-matter fibers colored by bundle. Anonymized sample, IMEKA/ANDI.
  • Corpus callosum 7
  • Association, dorsal 12
  • Association, ventral 8
  • Projection 4
  • Fornix 2

Up to 33 tracts 5 measures each Anonymized sample, IMEKA/ANDI

Up to 33 White-Matter Tracts Measured
5 Measures Per Tract
400K+ MRIs Interpreted
50 States Licensed
Tract by Tract

See which tracts fall outside their normative range.

Up to 33 white-matter tracts, checked one at a time against healthy reference data matched for age and sex. Only the tracts outside their range are flagged, each with the measurement behind it. Tracts that do not pass quality control are not scored.

Tract-by-tract check

One anonymized sample report

Corpus callosum

  • Anterior genu
  • Middle genu
  • Posterior genu AD 95.7
  • Anterior body
  • Posterior body Volume 4.0
  • Isthmus FA 96.4
  • Splenium FA 95.2 · AD 95.9

Fornix

  • Fornix LR

Projection

  • Corona radiata LR
  • Pyramidal tract LR

Association, ventral

  • IFOF LR
  • ILF LR
  • Optic radiation LR
  • Uncinate fasciculus LR

Association, dorsal

  • Arcuate fasciculus LR
  • Cingulum LR
  • Frontal aslant tract LR
  • SLF 1 L: Volume 2.0 LR
  • SLF 2 L: Volume 4.2 · R: FA 95.5 LR
  • SLF 3 LR

In this sample, 7 of 33 tracts fall outside their normative range: 4 on FA or AD, 3 on volume. Flag values are percentiles.

  • Within range
  • Outside range

Not every study has flagged tracts. A flag is a measurement to read in context, not a diagnosis. SLF: superior longitudinal fasciculus. IFOF: inferior fronto-occipital fasciculus. ILF: inferior longitudinal fasciculus.

THE DIFFERENCE

Visual DTI read vs. Advanced DTI

A visual read judges color tract maps by eye. Advanced DTI measures each tract and compares it with healthy reference data.

How tracts are judged
Visual read
Color tract maps read by eye
Advanced DTI
Each tract measured and compared statistically
Reference
Visual read
What looks typical to the reader
Advanced DTI
A normative range matched for age and sex
Result per tract
Visual read
A visual impression, with no number per tract
Advanced DTI
Up to 33 named tracts, each with its own measured result
Left-right color differences
Visual read
Can be over-read as a finding
Advanced DTI
Flags come from the statistics, not the colors
Who reads it
Visual read
May be read outside neuroradiology
Advanced DTI
A board-certified neuroradiologist reads and signs
Patient explanation
Visual read
Written for clinicians
Advanced DTI
A computer-generated plain-language summary for the patient

A visual DTI read means tract maps interpreted by eye, without per-tract statistics. The comparison is not based on any specific competing radiology service.

Inside the Report

What’s inside an Advanced DTI report.

Tract-level renderings and the normative comparison behind every flag. Every figure below comes from anonymized sample reports.

One white-matter bundle overlaid on brain MRI slices in four views: coronal, two sagittal and axial

Tract-level detail

Each measured bundle is rendered on the study it came from, so the finding has a place.

One bundle in four views. Anonymized sample, IMEKA/ANDI.

The top three out-of-range white matter bundles, shown in axial, sagittal and coronal views

Top out-of-range bundles, rendered

When tracts fall outside their range, the report renders the top three out-of-range bundles in three views, on the study they came from.

Top 3 out-of-range bundles. Anonymized sample, IMEKA/ANDI.

A table of five diffusion measures with percentile, value and normative range, above five charts plotting the patient's value against percentile bands by age

Measured against the normative range

Each bundle, and the white matter as a whole, is plotted for five measures (ADC, FA, AD, RD and volume) against healthy reference data, from the 5th to the 95th percentile.

Normative measures for the whole white matter. Anonymized sample, IMEKA/ANDI.

The bundles index: corpus callosum, fornix, projection, association dorsal and association ventral bundles, each with its color key

The 33-bundle atlas

Bundles are grouped as corpus callosum, association dorsal, fornix, projection and association ventral. This key belongs to the tract map, not to our brain illustration.

Bundles index. Anonymized sample, IMEKA/ANDI.

Live demo

See an Advanced DTI report in a live demo.

Schedule a demo, and we’ll walk you through an anonymized Advanced DTI report, tract by tract.

How We Read It

How Advanced DTI fits into the full brain MRI read.

Advanced DTI adds statistical evidence to a full neuroradiology read. It does not replace the conventional sequences, and it is not read from a picture.

  1. 01

    Conventional MRI

    T1, T2 and FLAIR images for structure and signal abnormality.

  2. 02

    Susceptibility-weighted imaging

    SWI to look for residual blood products.

  3. 03

    Diffusion tensor analysis

    Each tract measured and compared with healthy reference data by IMEKA’s ANDI.

  4. 04

    The neuroradiologist’s impression

    One signed report that weighs every sequence together.

A flagged tract is

  • a measurement outside the normative range for the patient’s age and sex
  • printed with its percentile, so anyone reading the report can check it
  • read in context with every other sequence in the study

A flagged tract is not, on its own

  • a diagnosis
  • proof of a specific injury or its cause
  • something to judge from left and right color differences on a tract map

Not every study comes back abnormal. When one does, the report names the tracts, gives the numbers and recommends clinical correlation.

How It Works

From scan to signed report.

Your team scans. ANDI measures each tract that passes quality control. A neuroradiologist reads the study and signs one PrecisionPlus v3™ report.

01

Scan with the approved protocol

Your technologists run the diffusion and T1 series on the protocol approved for ANDI and label the study for Advanced DTI.

02

ANDI measures each tract

IMEKA’s FDA-cleared ANDI software reconstructs the white-matter bundles and compares each one that passes quality control with healthy reference data matched for age and sex.

03

A neuroradiologist reads and signs

The neuroradiologist reviews the analysis alongside the conventional sequences and signs one PrecisionPlus v3™ report, with the full ANDI report included.

FAQs

Common Questions About
Advanced DTI.

What the analysis measures, who signs the report, and what a flag does and does not mean.

Advanced DTI adds tract-level diffusion tensor imaging analysis to a brain MRI read in PrecisionPlus v3™. IMEKA’s ANDI software measures up to 33 major white-matter tracts against healthy reference data matched for age and sex, and a board-certified neuroradiologist reads the study and signs the report.

A board-certified neuroradiologist reviews the ANDI analysis alongside the conventional MRI sequences and signs the report. The computer-generated plain-language summary for the patient is not reviewed by the radiologist and never replaces the radiologist’s report.

Yes. ANDI received FDA 510(k) clearance in July 2023 (K230913), and ANDI 2.0 in October 2025 (K252298). The clearance covers measuring white-matter tracts as adjunctive information. ANDI does not make a diagnosis; the neuroradiologist’s report does.

Standard DTI is the brain read with an illustration and a simple patient explanation. Advanced DTI adds the tract-by-tract analysis, the full IMEKA/ANDI report and a plain-language summary of the tractography findings.

No. Each tract is compared statistically against healthy reference data, and the report states what it found either way, including when every tract falls within its range.

An Advanced DTI report documents what the imaging demonstrates, tract by tract, with the measurements printed in the report. Whether and how it is used is for counsel and the court to decide. It does not establish legal causation, liability, or case valuation.

IMEKA/ANDI’s legend goes with the tract map. Our illustration key goes with the brain illustration and the patient summary. We keep them separate so each stays easy to read, and each applies only to its own section of the report.

Schedule a demo, and we’ll walk you through an anonymized Advanced DTI report.